What Clinical
Trials are Available at The Cancer Center?
NSABP
B-31: A
Phase III
Randomized
Clinical Trial Comparing Adriamycin and Cyclophosphamide
Followed by Taxol to Adriamycin and Cyclophosphamide Followed by
Taxol Plus Herceptin in Node-Positive Breast Cancer Patients
that Overexpress HER2
NSABP
B-35: A Phase III Clinical Trial Comparing Anastrozole with Tamoxifen in
Postmenopausal Women with Ductal Carcinoma In Situ Undergoing
Lumpectomy with Radiation Therapy.
CALGB
40101: A Phase III, 2 x 2 Factorial Randomized Research
Study for Women with Node-Negative Breast Cancer:
Doxorubicin and Cyclophosphamide (AC) (4 vs 6 Cycles)
Versus Paclitaxel (4 vs 6 Cycles) as Adjuvant Therapy.
NSABP
P-2: STAR - Study of Tamoxifen and Raloxifene in High-Risk
Postmenopausal Women.
NCIC CTG BR.19: Randomized
Phase III, Double-Blind, Placebo-Controlled Clinical Research
Trial of the Epidermal Growth Factor Receptor Antagonist, ZD1839
(IRESSA)
in Completely Resected Primary Stage IB, II and IIIA Non-Small
Cell Lung Cancer
Alpha
Oncology (A1-99002L): A
Randomized, Phase III Multicenter Trial of Gemcitabine in
Combination with Carboplatin or Paclitaxel versus Paclitaxel
plus Carboplatin in Patients with Metastatic (Stage IIIB, IV)
Non-Small Cell Lung Cancer.
Pharmacia
CPTAIV-0020-411: A
Randomized, Multi-center Phase III Research Trial of Irinotecan
in Combination with Three Different Methods of Administration of
Fluoropyrimidine: Infusional
5-FU (FOLFIRI), Bolus 5-FU (Day 1& 8), and Oral Capecitabine
(Day 1-14); with Celecoxib versus Placebo as First-line
Treatment for Patients with Metastatic Colorectal Cancer.
Glaxo Smith
Kline SK&F 104864-A/615:
An Open-Label, Multicenter, Randomized, Phase III Study Comparing
Combination IV Topotecan/Docetaxel To Docetaxel Alone In
Second-Line Advanced (IIIB/IV) Non-Small Cell Lung Cancer (NSCLC).
Lilly
H3E-US-JMFW: A
Randomized, Phase II Research Trial of ALIMTA/Cisplatin and
ALIMTA/Carboplatin in Extensive Stage Small Cell Lung Cancer.
Amgen
20020122: A
Randomized, Open Label, Multicenter Study of Primary Prophylaxis
with Pegfilgrastim Versus Secondary Prophylaxis as an Adjunct to
Chemotherapy in Elderly Subjects (65 years old) with Cancer.
LCCC
0204: A
Modified Phase I/II Research Trial of Weekly Docetaxel and
ZD1839 in
Elderly Patients with Stage IIIB/IV Non-Small Cell Lung
Cance
Non-Treatment
Studies
NSABP
Co-STAR: (Wake
Forest School of Medicine) – Effects of Selective Estrogen
Receptor Modulators on Cognitive Aging (STAR patients only).
CALGB
9665: Research
Study of Tissue Obtained from Untreated Patients Newly Diagnosed
with Acute/Chronic Leukemia or Myelodysplastic Syndrome.
Miscellaneous
Clinical Trials
UNC-School
of Public Health: The Carolina Head and Neck Cancer (CHANCE)
Study.
North
Carolina Melanoma Study: (00-EPID-32-0RC)
North
Carolina Ovarian Study: (575-99-4R2ER) Research Study of
Molecular Epidemiology of Ovarian Cancer.
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